Annotation Detail

Information
Associated Genes
MTRR
Associated Variants
MTRR MUTATION
MTRR MUTATION
Associated Disease
Down syndrome
Source Database
DisGeNET
Description
In conclusion, our meta-analysis suggested that the MTRR c.66A>G (rs1801394) polymorphism and MTHFD1 c.1958G>A (rs2236225) were associated with increased maternal risk for DS.
Pubmed
25544792
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
13
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0398248054139254
Drugs