Annotation Detail
Information
- Associated Genes
- CASP9
- Associated Variants
-
CASP9 MUTATION
CASP9 MUTATION - Associated Disease
- Down syndrome
- Source Database
- DisGeNET
- Description
- Cell senescence was found to appear prematurely in DS cells as shown by SA-β-Gal assay and p21 assessment, though not apoptosis, as neither p53 nor the proapoptotic proteins cytochrome c and caspase 9 were altered in T21F.
- Pubmed
- 25852816
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs