Annotation Detail
Information
- Associated Genes
- IL1A
- Associated Variants
-
IL1A MUTATION
IL1A MUTATION - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- These data provide the first in vivo evidence—using a transgenic mouse model with amyloid deposits resembling those found in human islets—that IAPP-induced beta cell dysfunction in type 2 diabetes may be mediated by IL-1.
- Pubmed
- 25491100
- Section of the abstract supporting the evidence
- CONCLUSIONS/INTERPRETATION
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0129968722514521
Drugs