Annotation Detail

Information
Associated Genes
TCF7L2
Associated Variants
TCF7L2 MUTATION
TCF7L2 MUTATION
Associated Disease
Diabetes Mellitus, Insulin-Dependent
Source Database
DisGeNET
Description
Interestingly, genetic signals from both T1D and T2D are also seen in LADA, including the key HLA and transcription factor 7-like 2 (TCF7L2) loci, but the magnitudes of these effects are more complex than just pointing to LADA as being a simple admixture of T1D and T2D.
Pubmed
25189437
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00399568321108385
Drugs