Annotation Detail
Information
- Associated Genes
- TLR2
- Associated Variants
-
TLR2 MUTATION
TLR2 MUTATION - Associated Disease
- dermatitis
- Source Database
- DisGeNET
- Description
- TLR2 activation in skin resident cells triggered interleukin-6 (IL-6), which induced suppressive MDSCs, which are then recruited to the skin suppressing T cell-mediated recall responses such as dermatitis.
- Pubmed
- 25456159
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
Drugs