Annotation Detail
Information
- Associated Genes
- CXCL5
- Associated Variants
-
CRP c.*1082G>A
(
ENST00000368112.5,
ENST00000437342.1,
ENST00000255030.9 )
CXCL5 p.Gln56= (p.Q56=) ( ENST00000296027.5 )
TNF c.-1037C>T
CRP c.*1082G>A ( ENST00000255030.9, ENST00000368112.5, ENST00000437342.1 )
CXCL5 p.Gln56= (p.Q56=) ( ENST00000296027.5 )
TNF c.-1037C>T - Associated Disease
- Malignant neoplasm of breast
- Source Database
- DisGeNET
- Description
- Among premenopausal AA women, comparing variant allele carriers to non-carriers, reduced breast cancer risk was associated with CXCL5-rs425535 (OR=0.61, P=0.02), while among EA women, there were associations with TNFA-rs1799724 (OR =2.31, P =0.002) and CRP-rs1205 (OR=0.54, P=0.01).
- Pubmed
- 23991131
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2013
Drugs