Annotation Detail
Information
- Associated Genes
- TGFB1
- Associated Variants
-
CCDC97 c.*986G>A
(
ENST00000269967.4 )
CCDC97 c.*1986T>C ( ENST00000269967.4 )
rs2808630
CRP c.*1082G>A ( ENST00000368112.5, ENST00000437342.1, ENST00000255030.9 )
CCDC97 c.*986G>A ( ENST00000269967.4 )
CCDC97 c.*1986T>C ( ENST00000269967.4 )
rs2808630
CRP c.*1082G>A ( ENST00000255030.9, ENST00000368112.5, ENST00000437342.1 ) - Associated Disease
- Chronic Obstructive Airway Disease
- Source Database
- DisGeNET
- Description
- Haplotype analysis showed that the frequencies of the GC, GT haplotypes of rs2241718 (TGF-β1 gene), and rs6957 (CDC97 gene) were significantly higher in the control group than in the COPD case group (p=1.88×10-9); the frequencies of the TT haplotype of rs1205 and rs2808630 (CRP gene) were significantly higher in the control group (p=0.0377).
- Pubmed
- 23267696
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.243744543754889
- Year of publication
- 2012
Drugs