Annotation Detail

Information
Associated Genes
IL23R
Associated Variants
IL23R MUTATION
IL23R MUTATION
Associated Disease
Colorectal Neoplasms
Source Database
DisGeNET
Description
These results suggest that TLR4, IL17A, IL17F and IL23R polymorphisms as well as the expression of microRNAs that regulate inflammation and the TH17 pathway are associated with the evolution and progression of the colorectal tumor that could be considered as biomarkers in colorectal cancer.
Pubmed
25911397
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
15
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs