Annotation Detail

Information
Associated Genes
NTRK2
Associated Variants
NTRK2 MUTATION
NTRK2 MUTATION
BDNF p.Val148Met (p.V148M) ( ENST00000532997.5, ENST00000395981.7, ENST00000356660.9, ENST00000314915.6, ENST00000439476.6, ENST00000530861.5, ENST00000395983.7, ENST00000395986.6, ENST00000525950.5, ENST00000533246.5, ENST00000418212.5, ENST00000525528.1, ENST00000533131.5, ENST00000395978.7, ENST00000438929.5 )
rs1187323 ( ENST00000686259.1, ENST00000686496.1, ENST00000686542.1, ENST00000689685.1, ENST00000691415.1, ENST00000692181.1, ENST00000692389.1, ENST00000692506.1, ENST00000692804.1, ENST00000693109.1, ENST00000693539.1 )
BDNF SNV ( ENST00000686259.1, ENST00000686496.1, ENST00000686542.1, ENST00000689685.1, ENST00000691415.1, ENST00000692181.1, ENST00000692389.1, ENST00000692506.1, ENST00000692804.1, ENST00000693109.1, ENST00000693539.1 )
NTRK2 c.212+3405A>G ( ENST00000277120.8, ENST00000304053.11, ENST00000323115.11, ENST00000359847.4, ENST00000376208.6, ENST00000376213.6, ENST00000395882.6, ENST00000685387.1, ENST00000685720.1, ENST00000686259.1, ENST00000686322.1, ENST00000686324.1, ENST00000686443.1, ENST00000686496.1, ENST00000686542.1, ENST00000687148.1, ENST00000687386.1, ENST00000687596.1, ENST00000687636.1, ENST00000688013.1, ENST00000689301.1, ENST00000689685.1, ENST00000689815.1, ENST00000690281.1, ENST00000691415.1, ENST00000691788.1, ENST00000692181.1, ENST00000692389.1, ENST00000692473.1, ENST00000692506.1, ENST00000692762.1, ENST00000692804.1, ENST00000693109.1, ENST00000693127.1, ENST00000693384.1, ENST00000693539.1 )
NTRK2 c.360-219T>C ( ENST00000277120.8, ENST00000304053.11, ENST00000323115.11, ENST00000359847.4, ENST00000376208.6, ENST00000376213.6, ENST00000395882.6, ENST00000685387.1, ENST00000685720.1, ENST00000686259.1, ENST00000686322.1, ENST00000686324.1, ENST00000686443.1, ENST00000686496.1, ENST00000686542.1, ENST00000687148.1, ENST00000687386.1, ENST00000687596.1, ENST00000687636.1, ENST00000688013.1, ENST00000689301.1, ENST00000689685.1, ENST00000689815.1, ENST00000690281.1, ENST00000691415.1, ENST00000691788.1, ENST00000692181.1, ENST00000692389.1, ENST00000692473.1, ENST00000692506.1, ENST00000692762.1, ENST00000692804.1, ENST00000693109.1, ENST00000693127.1, ENST00000693384.1, ENST00000693539.1 )
NTRK2 c.1634-6708G>T ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
BDNF p.Val148Met (p.V148M) ( ENST00000314915.6, ENST00000356660.9, ENST00000395978.7, ENST00000395981.7, ENST00000395983.7, ENST00000395986.6, ENST00000418212.5, ENST00000438929.5, ENST00000439476.6, ENST00000525528.1, ENST00000525950.5, ENST00000530861.5, ENST00000532997.5, ENST00000533131.5, ENST00000533246.5 )
rs1187323 ( ENST00000686259.1, ENST00000686496.1, ENST00000686542.1, ENST00000689685.1, ENST00000691415.1, ENST00000692181.1, ENST00000692389.1, ENST00000692506.1, ENST00000692804.1, ENST00000693109.1, ENST00000693539.1 )
BDNF SNV ( ENST00000686259.1, ENST00000686496.1, ENST00000686542.1, ENST00000689685.1, ENST00000691415.1, ENST00000692181.1, ENST00000692389.1, ENST00000692506.1, ENST00000692804.1, ENST00000693109.1, ENST00000693539.1 )
NTRK2 c.212+3405A>G ( ENST00000277120.8, ENST00000304053.11, ENST00000323115.11, ENST00000359847.4, ENST00000376208.6, ENST00000376213.6, ENST00000395882.6, ENST00000685387.1, ENST00000685720.1, ENST00000686259.1, ENST00000686322.1, ENST00000686324.1, ENST00000686443.1, ENST00000686496.1, ENST00000686542.1, ENST00000687148.1, ENST00000687386.1, ENST00000687596.1, ENST00000687636.1, ENST00000688013.1, ENST00000689301.1, ENST00000689685.1, ENST00000689815.1, ENST00000690281.1, ENST00000691415.1, ENST00000691788.1, ENST00000692181.1, ENST00000692389.1, ENST00000692473.1, ENST00000692506.1, ENST00000692762.1, ENST00000692804.1, ENST00000693109.1, ENST00000693127.1, ENST00000693384.1, ENST00000693539.1 )
NTRK2 c.360-219T>C ( ENST00000277120.8, ENST00000304053.11, ENST00000323115.11, ENST00000359847.4, ENST00000376208.6, ENST00000376213.6, ENST00000395882.6, ENST00000685387.1, ENST00000685720.1, ENST00000686259.1, ENST00000686322.1, ENST00000686324.1, ENST00000686443.1, ENST00000686496.1, ENST00000686542.1, ENST00000687148.1, ENST00000687386.1, ENST00000687596.1, ENST00000687636.1, ENST00000688013.1, ENST00000689301.1, ENST00000689685.1, ENST00000689815.1, ENST00000690281.1, ENST00000691415.1, ENST00000691788.1, ENST00000692181.1, ENST00000692389.1, ENST00000692473.1, ENST00000692506.1, ENST00000692762.1, ENST00000692804.1, ENST00000693109.1, ENST00000693127.1, ENST00000693384.1, ENST00000693539.1 )
NTRK2 c.1634-6708G>T ( ENST00000277120.8, ENST00000323115.11, ENST00000376213.6, ENST00000686259.1, ENST00000686324.1, ENST00000686496.1, ENST00000687386.1, ENST00000689301.1, ENST00000691788.1, ENST00000692181.1, ENST00000692473.1 )
Associated Disease
Unipolar Depression
Source Database
DisGeNET
Description
We genotyped the BDNF gene Val66Met (rs6265) polymorphism and four single-nucleotide polymorphisms (SNPs) (including rs1187323, rs1187329, rs1778929, and rs1545285) in the NTRK2 gene in 155 elderly inpatients diagnosed with major depression and 195 age- and sex-similar control subjects.
Pubmed
20014955
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Year of publication
2009
Drugs