Annotation Detail

Information
Associated Genes
MAPK1
Associated Variants
MAPK1 MUTATION
MAPK1 MUTATION
Associated Disease
Colorectal Neoplasms
Source Database
DisGeNET
Description
Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87.
Pubmed
25826088
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree,LHGDN
DisGENET score for the Gene Disease association
0.00599158422909495
Drugs