Annotation Detail
Information
- Associated Genes
- FGFR1
- Associated Variants
-
FGFR1 MUTATION
FGFR1 MUTATION - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- AZD-4547 was cytotoxic and pro-apoptotic in FGFR-1/2-expressed CRC cell lines (NCI-H716 and HCT-116), but not in FGFR-1/2 null HT-29 cells.
- Pubmed
- 25691251
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs