Annotation Detail
Information
- Associated Genes
- IGF1
- Associated Variants
-
IGF1 MUTATION
IGF1 MUTATION - Associated Disease
- colorectal carcinoma
- Source Database
- DisGeNET
- Description
- These data suggested that inhibiting cytohesins or ARNO as cytoplasmic activators of EGFR and IGF-I in colorectal cancer resulted in anti-proliferation, reduced invasion, decreased migration, and suppressed growth in vivo and in vitro.
- Pubmed
- 24618737
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00760037241824849
Drugs