Annotation Detail

Information
Associated Genes
TLR2
Associated Variants
TLR2 MUTATION
TLR2 MUTATION
Associated Disease
colitis
Source Database
DisGeNET
Description
Our results indicate that S. Typhimurium ΔmsbB triggers exacerbated colitis in the absence of Nod1 and/or Nod2, which is likely due to increased TLR2 stimulation.
Pubmed
25423082
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
14
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00190009310456212
Drugs