Annotation Detail

Information
Associated Genes
NR1I2
Associated Variants
NR1I2 MUTATION
NR1I2 MUTATION
Associated Disease
cholestasis
Source Database
DisGeNET
Description
The in vivo experiments using PXR siRNA revealed that Tan IIA could protect against LCA-induced hepatotoxicity and cholestasis in a dose-dependent manner.
Pubmed
25660334
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs