Annotation Detail
Information
- Associated Genes
- TLR1
- Associated Variants
-
TLR1 MUTATION
TLR1 MUTATION - Associated Disease
- Chediak-Higashi syndrome
- Source Database
- DisGeNET
- Description
- At baseline, we found CD14, IL1R1 and TLR-1 were down-regulated significantly (≥2 fold change) and the genes encoding TLR-3, IL-1β and IL-6 were up-regulated in CHS cells compared to control cells.
- Pubmed
- 25528552
- Section of the abstract supporting the evidence
- METHODS AND RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs