Annotation Detail
Information
- Associated Genes
- CASP8
- Associated Variants
-
CASP8 MUTATION
CASP8 MUTATION - Associated Disease
- Malignant tumor of cervix
- Source Database
- DisGeNET
- Description
- Here, we show that Mith decreased Sp1 protein by inducing proteasome-dependent degradation, thereby suppressing cervical cancer growth through a DR5/caspase-8/Bid signaling pathway.
- Pubmed
- 25418289
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs