Annotation Detail

Information
Associated Genes
TNF
Associated Variants
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
TNF c.-488G>A
IL1A p.Ala114Ser (p.A114S) ( ENST00000263339.4 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
TNF c.-488G>A
Associated Disease
Migraine Disorders
Source Database
DisGeNET
Description
In this study, the association of the occurrence and clinical characteristics of migraine with the polymorphisms of tumor necrosis factor alpha (TNF-alpha) -308 G/A (rs1800629), interleukin-1alpha (IL-1alpha) +4845 G/T (rs17561), IL-1beta+3953 C/T (rs1143634) and interleukin-1 receptor antagonist variable number tandem repeat (IL-1RA VNTR) genes were studied.
Pubmed
20113413
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.138902580088762
Year of publication
2010
Drugs