Annotation Detail
Information
- Associated Genes
- IL1B
- Associated Variants
-
IL16 c.1420+258G>T
(
ENST00000683961.1,
ENST00000302987.10,
ENST00000394660.6,
ENST00000706926.1 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
rs662959
rs1881457
IL16 c.1420+258G>T ( ENST00000302987.10, ENST00000394660.6, ENST00000683961.1, ENST00000706926.1 )
IL1B p.Phe105= (p.F105=) ( ENST00000263341.7 )
rs662959
rs1881457 - Associated Disease
- Carcinoma of lung
- Source Database
- DisGeNET
- Description
- CART analyses did not yield a tree structure for overall survival; separate CART tree structures were identified for recurrence, based on three SNPs (IL13:rs1881457, IL1B:rs1143634, and IL12A:rs662959), and for disease-free survival, based on two SNPs (IL12A:rs662959 and IL16:rs7170924), which may suggest that these candidate IL SNPs have a specific impact on lung cancer progression and recurrence.
- Pubmed
- 25597281
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00461451182536516
- Year of publication
- 2014
Drugs