Annotation Detail

Information
Associated Genes
POLG
Associated Variants
POLG p.Trp748Ser (p.W748S) ( ENST00000442287.6, ENST00000636937.2, ENST00000268124.11 )
POLG p.Trp748Ser (p.W748S) ( ENST00000268124.11, ENST00000442287.6, ENST00000636937.2 )
Associated Disease
Parkinsonian Disorders
Source Database
DisGeNET
Description
Parkinsonism associated with the homozygous W748S mutation in the POLG1 gene.
Pubmed
18321754
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.140417729536008
Year of publication
2008
Drugs