Annotation Detail

Information
Associated Genes
LEPR
Associated Variants
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000371058.1, ENST00000371060.7, ENST00000616738.4, ENST00000371059.7, ENST00000349533.11 )
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000349533.11, ENST00000371058.1, ENST00000371059.7, ENST00000371060.7, ENST00000616738.4 )
Associated Disease
obesity
Source Database
DisGeNET
Description
The Q223R polymorphism of the leptin receptor gene is significantly associated with obesity and predicts a small percentage of body weight and body composition variability.
Pubmed
11549688
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.640987722684126
Year of publication
2001
Drugs