Annotation Detail
Information
- Associated Genes
- ERCC4
- Associated Variants
-
ERCC4 MUTATION
ERCC4 MUTATION - Associated Disease
- squamous cell carcinoma
- Source Database
- DisGeNET
- Description
- Patients with the other genotypes (FANCA through FANCQ) have cumulative risks of more than 50% of marrow failure, 20% of AML, and 30% of solid tumors (usually head and neck or gynecologic squamous cell carcinoma), by age 40, and they too are at risk of multiple adverse events.
- Pubmed
- 25455269
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs