Annotation Detail
Information
- Associated Genes
- LEPR
- Associated Variants
-
LEPR p.Gln223Arg (p.Q223R)
(
ENST00000344610.12,
ENST00000371058.1,
ENST00000371060.7,
ENST00000616738.4,
ENST00000371059.7,
ENST00000349533.11 )
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000349533.11, ENST00000371058.1, ENST00000371059.7, ENST00000371060.7, ENST00000616738.4 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- The haplotype combination of LEP c.-2548G>A and LEPR p.Q223R variants was related to a 58% increase in obesity risk.
- Pubmed
- 18273796
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.640987722684126
- Year of publication
- 2007
Drugs