Annotation Detail

Information
Associated Genes
LEPR
Associated Variants
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000371058.1, ENST00000371060.7, ENST00000616738.4, ENST00000371059.7, ENST00000349533.11 )
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000349533.11, ENST00000371058.1, ENST00000371059.7, ENST00000371060.7, ENST00000616738.4 )
Associated Disease
Amebic colitis
Source Database
DisGeNET
Description
Humans with the Q223R leptin receptor mutation have increased susceptibility to amebiasis, but the mechanism has been unclear.
Pubmed
25516614
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2015
Drugs