Annotation Detail

Information
Associated Genes
LEPR
Associated Variants
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000371058.1, ENST00000371060.7, ENST00000616738.4, ENST00000371059.7, ENST00000349533.11 )
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000349533.11, ENST00000371058.1, ENST00000371059.7, ENST00000371060.7, ENST00000616738.4 )
Associated Disease
obesity
Source Database
DisGeNET
Description
Obesity-related genetic factors including common polymorphisms in the leptin gene (LEP A19G and G-2548A) and its receptor (LEPR Q223R) were investigated in DNA available for 376 patients and 805 controls.
Pubmed
15159310
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.640987722684126
Year of publication
2004
Drugs