Annotation Detail
Information
- Associated Genes
- LEP
- Associated Variants
-
AGT c.-158A>G
(
ENST00000680783.1,
ENST00000681269.1,
ENST00000679684.1,
ENST00000366667.6,
ENST00000679957.1,
ENST00000681514.1,
ENST00000680041.1 )
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000371058.1, ENST00000371060.7, ENST00000616738.4, ENST00000371059.7, ENST00000349533.11 )
AGT c.-158A>G ( ENST00000366667.6, ENST00000679684.1, ENST00000679957.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000681514.1 )
LEPR p.Gln223Arg (p.Q223R) ( ENST00000344610.12, ENST00000349533.11, ENST00000371058.1, ENST00000371059.7, ENST00000371060.7, ENST00000616738.4 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- All the individuals were genotyped for the following subset of polymorphisms in obesity-related genes: angiotensinogen gene (M235T and -6A/G), in IL-6 gene (-174 G/C and -596 A/G), in leptin gene (-2548 A/G), and polymorphism Gln223Arg within the leptin receptor (LEPR) gene.
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.44
- Year of publication
- 2009
- Pubmed
- 18704460
Drugs