Annotation Detail

Information
Associated Genes
GAA
Associated Variants
GAA p.Glu471ProfsTer5 (p.E471Pfs*5) ( ENST00000714054.1, ENST00000577106.6, ENST00000714057.1, ENST00000714062.1, ENST00000570803.6, ENST00000390015.7, ENST00000714058.1, ENST00000302262.8, ENST00000714055.1 )
GAA p.Glu471ProfsTer5 (p.E471Pfs*5) ( ENST00000302262.8, ENST00000390015.7, ENST00000570803.6, ENST00000577106.6, ENST00000714054.1, ENST00000714055.1, ENST00000714057.1, ENST00000714058.1, ENST00000714062.1 )
Associated Disease
not provided
Source Database
ClinVar
Description
NM_000152.5(GAA):c.1411_1414del (p.Glu471fs) AND not provided
ClinVar Allele ID
187002
ClinVar RefSeq Alternation Syntax
NM_001079804.3:c.1411_1414del
ClinVar RefSeq Alternation Syntax
NM_001079803.3:c.1411_1414del
ClinVar RefSeq Alternation Syntax
NM_000152.5:c.1411_1414del
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2019-10-29
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV001781522
ClinVar Disease
not provided
Observed Origin Sample
germline
Drugs