Annotation Detail

Information
Associated Genes
BRAF
Associated Variants
BRAF p.Ala752Asp (p.A752D) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
BRAF p.Ala752Asp (p.A752D) ( ENST00000288602.11, ENST00000496384.7, ENST00000644969.2, ENST00000646891.2 )
Associated Disease
not provided
Source Database
ClinVar
Description
NM_004333.6(BRAF):c.2135C>A (p.Ala712Asp) AND not provided
ClinVar Allele ID
174175
ClinVar RefSeq Alternation Syntax
NM_001378470.1:c.2033C>A
ClinVar RefSeq Alternation Syntax
NM_001378468.1:c.2127+5049C>A
ClinVar RefSeq Alternation Syntax
NM_001378471.1:c.2024C>A
ClinVar RefSeq Alternation Syntax
NM_004333.6:c.2135C>A
ClinVar RefSeq Alternation Syntax
NM_001378475.1:c.1871C>A
ClinVar RefSeq Alternation Syntax
NM_001378469.1:c.2069C>A
ClinVar RefSeq Alternation Syntax
NM_001374258.1:c.2255C>A
ClinVar RefSeq Alternation Syntax
NM_001378473.1:c.1979C>A
ClinVar RefSeq Alternation Syntax
NM_001378472.1:c.1979C>A
ClinVar RefSeq Alternation Syntax
NM_001354609.2:c.2135C>A
ClinVar RefSeq Alternation Syntax
NM_001374244.1:c.2255C>A
ClinVar RefSeq Alternation Syntax
NM_001378467.1:c.2144C>A
ClinVar RefSeq Alternation Syntax
NM_001378474.1:c.2127+5049C>A
Clinical Significance Description
Pathogenic/Likely pathogenic
Clinical Significance Last Update
2021-09-23
Clinical Significance Review Status
criteria provided, multiple submitters, no conflicts
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000788373
ClinVar Disease
not provided
Observed Origin Sample
germline
Drugs