Annotation Detail

Information
Associated Genes
VHL
Associated Variants
VHL p.Ser65Trp (p.S65W) ( ENST00000713815.1, ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713982.1 )
VHL p.Ser65Trp (p.S65W) ( ENST00000256474.3, ENST00000345392.3, ENST00000696143.2, ENST00000696153.1, ENST00000713811.1, ENST00000713812.1, ENST00000713815.1, ENST00000713982.1 )
Associated Disease
not provided
Source Database
ClinVar
Description
NM_000551.4(VHL):c.194C>G (p.Ser65Trp) AND not provided
ClinVar Allele ID
52766
ClinVar RefSeq Alternation Syntax
NM_001354723.2:c.194C>G
ClinVar RefSeq Alternation Syntax
NM_000551.4:c.194C>G
ClinVar RefSeq Alternation Syntax
NM_198156.3:c.194C>G
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2023-08-15
Clinical Significance Review Status
criteria provided, multiple submitters, no conflicts
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000497340
ClinVar Disease
not provided
Observed Origin Sample
germline
Drugs