Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS p.Gly60Glu (p.G60E) ( ENST00000369535.5 )
NRAS p.Gly60Glu (p.G60E) ( ENST00000369535.5 )
Associated Disease
Noonan syndrome 6
Source Database
ClinVar
Description
NM_002524.5(NRAS):c.179G>A (p.Gly60Glu) AND Noonan syndrome 6
ClinVar Allele ID
28942
ClinVar RefSeq Alternation Syntax
NM_002524.5:c.179G>A
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2017-08-01
Clinical Significance Review Status
criteria provided, single submitter
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000014917
ClinVar Disease
Noonan syndrome 6
Observed Origin Sample
germline
Pubmed
26467218
Pubmed
19966803
Drugs