Annotation Detail

Information
Associated Genes
KIT
Associated Variants
KIT p.Lys551_Lys559del (p.K551_K559del) ( ENST00000288135.6, ENST00000412167.7, ENST00000686011.1, ENST00000687109.1, ENST00000687246.1, ENST00000687295.1, ENST00000689832.1, ENST00000689994.1, ENST00000690543.1, ENST00000692783.1 )
KIT p.Lys551_Lys559del (p.K551_K559del) ( ENST00000288135.6, ENST00000412167.7, ENST00000686011.1, ENST00000687109.1, ENST00000687246.1, ENST00000687295.1, ENST00000689832.1, ENST00000689994.1, ENST00000690543.1, ENST00000692783.1 )
Associated Disease
gastrointestinal stromal tumor
Source Database
ClinVar
Description
NM_000222.2(KIT):c.1648_1674del AND Gastrointestinal stromal tumor
ClinVar Allele ID
28896
Clinical Significance Description
Pathogenic
Clinical Significance Last Update
2005-06-16
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000014871
ClinVar Disease
Gastrointestinal stromal tumor
Observed Origin Sample
somatic
Pubmed
15824741
Pubmed
9438854
Drugs