Annotation Detail

Information
Associated Genes
IL23R
Associated Variants
IL23R p.Arg381Gln (p.R381Q) ( ENST00000697230.1, ENST00000697164.1, ENST00000697163.1, ENST00000697154.1, ENST00000425614.3, ENST00000347310.10, ENST00000697165.1 )
IL23R p.Arg381Gln (p.R381Q) ( ENST00000347310.10, ENST00000425614.3, ENST00000697154.1, ENST00000697163.1, ENST00000697164.1, ENST00000697165.1, ENST00000697230.1 )
Associated Disease
Inflammatory bowel disease 17, protection against
Source Database
ClinVar
Description
NM_144701.3(IL23R):c.1142G>A (p.Arg381Gln) AND Inflammatory bowel disease 17, protection against
ClinVar Allele ID
18147
ClinVar RefSeq Alternation Syntax
NM_144701.3:c.1142G>A
Clinical Significance Description
protective
Clinical Significance Last Update
2010-04-01
Clinical Significance Review Status
no assertion criteria provided
URL
https://www.ncbi.nlm.nih.gov/clinvar/RCV000003254
ClinVar Disease
Inflammatory bowel disease 17, protection against
Observed Origin Sample
germline
Pubmed
17786191
Pubmed
18438406
Pubmed
12023369
Pubmed
17587057
Pubmed
17447842
Pubmed
19122664
Pubmed
17068223
Pubmed
17804789
Pubmed
20228799
Drugs