Annotation Detail
Information
- Associated Genes
- FGFR1
- Associated Variants
-
FGFR1 AMPLIFICATION
(
ENST00000425967.8 )
FGFR1 AMPLIFICATION ( ENST00000425967.8 ) - Associated Disease
- lung squamous cell carcinoma
- Source Database
- CIViC Evidence
- Description
- In this study in surgically resected squamous cell lung cancer, FGFR1 amplification has been shown as an independent negative prognostic factor in Asian patients. FGFR1 amplification also correlates with cigarette smoking.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/682
- Gene URL
- https://civic.genome.wustl.edu/links/genes/1885
- Variant URL
- https://civic.genome.wustl.edu/links/variants/267
- Rating
- 4
- Evidence Type
- Prognostic
- Disease
- Lung Squamous Cell Carcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 23182986
Drugs