lung squamous cell carcinoma (Cancer)
Information
- Disease name
- lung squamous cell carcinoma
- Disease ID
- DOID:3907
- Description
- "A non-small cell lung carcinoma that has_material_basis_in the squamous cell." [url:http\://cancergenome.nih.gov/cancersselected/lungsquamouscell, url:http\://en.wikipedia.org/wiki/Squamous-cell_carcinoma, url:http\://en.wikipedia.org/wiki/Squamous_cell_carcinoma_of_the_lung, url:http\://www.cancer.gov/dictionary?CdrID=46595]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| TP53 | 17 | 7,668,421 | 7,687,490 | 6 |
| KEAP1 | 19 | 10,486,126 | 10,502,896 | 6 |
| NOTCH1 | 9 | 136,494,433 | 136,546,048 | 4 |
| FAT1 | 4 | 186,587,794 | 186,723,856 | 4 |
| JAK3 | 19 | 17,824,782 | 17,847,982 | 4 |
| SOX2-OT | 3 | 180,989,779 | 181,742,884 | 4 |
| SOX2 | 3 | 181,711,925 | 181,714,436 | 4 |
| H3C14 | 1 | 149,840,687 | 149,841,208 | 4 |
| RBL1 | 20 | 36,996,349 | 37,095,997 | 2 |
| KDM5A | 12 | 280,057 | 389,320 | 2 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT04152018 | Active, not recruiting | Phase 1 | Study of PF-06940434 in Patients With Advanced or Metastatic Solid Tumors. | November 13, 2019 | August 30, 2024 |
| NCT01386385 | Active, not recruiting | Phase 1/Phase 2 | Veliparib With or Without Radiation Therapy, Carboplatin, and Paclitaxel in Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery | June 20, 2011 | December 31, 2024 |
| NCT00334815 | Active, not recruiting | Phase 2 | Combination Chemotherapy, Radiation Therapy, and Bevacizumab in Treating Patients With Newly Diagnosed Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery | June 15, 2006 | February 22, 2025 |
| NCT01807546 | Completed | Phase 2 | Oral Rigosertib for Squamous Cell Carcinoma | March 2013 | April 2016 |
| NCT06436040 | Recruiting | Mechanism Study to Investigate Difference in Efficacy of Neoadjuvant Chemoimmunotherapy in Lung Squamous Cell Carcinoma | January 24, 2024 | May 16, 2025 | |
| NCT04802876 | Recruiting | Phase 2 | Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients With PD1-high mRNA Expressing Tumors | April 12, 2021 | March 31, 2027 |
| NCT05778253 | Recruiting | The Role of ctDNA Testing Plus AI-based Pathology in Resectable LSCC | March 23, 2023 | September 23, 2029 | |
| NCT05782764 | Recruiting | Phase 4 | A Study of Endostar Combined With Chemotherapy and Immunotherapy in Lung Squamous Cell Carcinom | June 1, 2023 | May 30, 2025 |
| NCT06255197 | Recruiting | Characteristics, Treatment Patterns and Outcomes for Patients With Surgically Resected Lung Cancers | November 4, 2019 | December 31, 2031 | |
| NCT05010330 | Unknown status | Identify Prognostic Biomarkers of Lung Cancer | July 1, 2020 | September 30, 2021 | |
| NCT05024266 | Unknown status | Phase 2 | Tislelizumab Combined With Chemotherapy as Neoadjuvant Therapy for Stage IIIA-IIIB (N2) Lung Squamous Cell Carcinoma | August 1, 2021 | August 31, 2023 |
| NCT04132102 | Unknown status | Phase 4 | To Evaluate the Efficacy of Afatinib in Advanced Lung Squamous Cell Carcinoma With EGFR Sensitive Mutation | November 27, 2018 | August 31, 2021 |
| NCT03725423 | Unknown status | Phase 4 | Apatinib for Advanced Lung Squmamous Carcinoma | October 2018 | June 2019 |
| NCT02876978 | Unknown status | Phase 1 | Anti-GPC3 CAR T for Recurrent or Refractory Lung Squamous Cell Carcinoma | March 2016 | April 2019 |
| NCT04267913 | Withdrawn | Phase 2 | Testing of TAK228 (MLN0128, Sapanisertib) Plus Docetaxel to the Usual Standard of Care for Advanced Squamous Cell Lung Cancer (A Lung-MAP Treatment Trial) | September 5, 2020 | October 31, 2026 |
- Disase is a (Disease Ontology)
- DOID:3908
- Cross Reference ID (Disease Ontology)
- NCI:C3493
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:254634000
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0149782
- Exact Synonym (Disease Ontology)
- Epidermoid cell carcinoma of the lung
- Disase Synonym (Disease Ontology)
- squamous cell carcinoma of lung