Annotation Detail
Information
- Associated Genes
- CALR
- Associated Variants
-
CALR MUTATION
CALR MUTATION - Associated Disease
- essential thrombocythemia
- Source Database
- CIViC Evidence
- Description
- Diagnostic criterion for essential thrombocytemia according to the World Health Organization (WHO) classification of tumors of the hematopoietic and lymphoid tissues 2016.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/6382
- Gene URL
- https://civic.genome.wustl.edu/links/genes/732
- Variant URL
- https://civic.genome.wustl.edu/links/variants/2388
- Rating
- 5
- Evidence Type
- Diagnostic
- Disease
- Essential Thrombocythemia
- Evidence Direction
- Supports
- Evidence Level
- A
- Clinical Significance
- Positive
- Pubmed
- 27069254
Drugs