Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS Q61
NRAS Q61
Associated Disease
thyroid gland follicular carcinoma
Source Database
CIViC Evidence
Description
In patients with follicular thyroid carcinoma, those with mutations in NRAS at codon 61 did not have significantly different overall survival than patients with wild-type NRAS (p=0.36).
Variant Origin
somatic
Variant Origin
Somatic
Evidence URL
https://civic.genome.wustl.edu/links/evidence_items/497
Gene URL
https://civic.genome.wustl.edu/links/genes/36
Variant URL
https://civic.genome.wustl.edu/links/variants/94
Rating
3
Evidence Type
Prognostic
Disease
Follicular Thyroid Carcinoma
Evidence Direction
Supports
Evidence Level
B
Clinical Significance
N/A
Pubmed
22650231
Drugs