Annotation Detail

Information
Associated Genes
NRAS
Associated Variants
NRAS MUTATION
NRAS MUTATION
Associated Disease
multiple myeloma
Source Database
CIViC Evidence
Description
In patients with multiple myeloma, the presence of a mutation in NRAS was not significantly associated with progression-free or overall survival.
Variant Origin
somatic
Variant Origin
Somatic
Evidence URL
https://civic.genome.wustl.edu/links/evidence_items/496
Gene URL
https://civic.genome.wustl.edu/links/genes/36
Variant URL
https://civic.genome.wustl.edu/links/variants/208
Rating
4
Evidence Type
Prognostic
Disease
Multiple Myeloma
Evidence Direction
Supports
Evidence Level
B
Clinical Significance
N/A
Pubmed
18528420
Drugs