Annotation Detail
Information
- Associated Genes
- EGFR
- Associated Variants
-
EGFR OVEREXPRESSION
(
ENST00000275493.7 )
EGFR OVEREXPRESSION ( ENST00000275493.7 ) - Associated Disease
- brain glioblastoma multiforme
- Source Database
- CIViC Evidence
- Description
- In patients with glioblastoma multiforme, those with overespression of wild-type EGFR had shorter overall survival.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/474
- Gene URL
- https://civic.genome.wustl.edu/links/genes/19
- Variant URL
- https://civic.genome.wustl.edu/links/variants/193
- Rating
- 3
- Evidence Type
- Prognostic
- Disease
- Supratentorial Glioblastoma Multiforme
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 14583498
Drugs