Annotation Detail
Information
- Associated Genes
- BAP1
- Associated Variants
-
BAP1 MUTATION
BAP1 MUTATION - Associated Disease
- clear cell renal cell carcinoma
- Source Database
- CIViC Evidence
- Description
- In patients with clear cell renal cell carcinoma, in a multivariate analysis those with mutations in BAP1 had worse overall survival than wild-type.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/459
- Gene URL
- https://civic.genome.wustl.edu/links/genes/70
- Variant URL
- https://civic.genome.wustl.edu/links/variants/183
- Rating
- 5
- Evidence Type
- Prognostic
- Disease
- Clear Cell Renal Cell Carcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 23797736
Drugs