Annotation Detail
Information
- Associated Genes
- AURKA
- Associated Variants
-
AURKA EXPRESSION
AURKA EXPRESSION - Associated Disease
- ovarian carcinoma
- Source Database
- CIViC Evidence
- Description
- In patients with ovarian carcinomas, those with Aurora kinase A expression (as measured by immunohistochemistry) had increased progression-free and overall survival compared to those without expression.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/416
- Gene URL
- https://civic.genome.wustl.edu/links/genes/61
- Variant URL
- https://civic.genome.wustl.edu/links/variants/158
- Rating
- 3
- Evidence Type
- Prognostic
- Disease
- Ovarian Carcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Better Outcome
- Pubmed
- 19157502
Drugs