Annotation Detail
Information
- Associated Genes
- CCND1
- Associated Variants
-
CCND1 OVEREXPRESSION
(
ENST00000227507.3 )
CCND1 OVEREXPRESSION ( ENST00000227507.3 ) - Associated Disease
- head and neck squamous cell carcinoma
- Source Database
- CIViC Evidence
- Description
- Cyclin D1 overexpression is associated with shorter overall survival and increased metastasis in head and neck squamous cell carcinoma.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/357
- Gene URL
- https://civic.genome.wustl.edu/links/genes/8
- Variant URL
- https://civic.genome.wustl.edu/links/variants/20
- Rating
- 4
- Evidence Type
- Prognostic
- Disease
- Head And Neck Squamous Cell Carcinoma
- Evidence Direction
- Supports
- Evidence Level
- B
- Clinical Significance
- Poor Outcome
- Pubmed
- 16309541
Drugs