Annotation Detail
Information
- Associated Genes
- WT1
- Associated Variants
-
WT1 EXON 7 MUTATION
WT1 EXON 7 MUTATION - Associated Disease
- acute myeloid leukemia
- Source Database
- CIViC Evidence
- Description
- No differences in relapse-free or overall survival were identified between young (16-60) patients with or without WT1 mutations (69% exon 7, 15% exon 9) in cytogenetically normal AML.
- Variant Origin
- somatic
- Variant Origin
- Somatic
- Evidence URL
- https://civic.genome.wustl.edu/links/evidence_items/162
- Gene URL
- https://civic.genome.wustl.edu/links/genes/49
- Variant URL
- https://civic.genome.wustl.edu/links/variants/129
- Rating
- 3
- Evidence Type
- Prognostic
- Disease
- Acute Myeloid Leukemia
- Evidence Direction
- Does Not Support
- Evidence Level
- B
- Clinical Significance
- N/A
- Pubmed
- 19221039
Drugs