chr10:43077068:> Detail (hg38) (RET)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr10:43,572,516-43,625,799 |
| hg38 | chr10:43,077,068-43,130,351 |
HGVS
| Type | Transcript | Protein |
|---|---|---|
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
Frequency
[No Data.]
Prediction
[No Data.]
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| lung non-small cell carcinoma | Cabozantinib | B |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 27825636 | Detail |
| lung non-small cell carcinoma | Vandetanib | B |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 27803005 | Detail |
| lung non-small cell carcinoma | Vandetanib | B |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 27825616 | Detail |
| lung non-small cell carcinoma | Alectinib | B |
Predictive
|
Supports
|
Sensitivity/Response | Somatic | 3 | 27544060 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| RET rearrangements are found in 1-2% of non-small-cell lung cancers. Cabozantinib is a multikinase i... | CIViC Evidence | Detail |
| RET rearrangements involving RET are found in about 1% of NSCLC and define a unique molecular subset... | CIViC Evidence | Detail |
| We aimed to assess the efficacy and safety of vandetanib in patients with advanced RET-rearranged NS... | CIViC Evidence | Detail |
| Alectinib is an anaplastic lymphoma kinase tyrosine kinase inhibitor (TKI) that also has anti-RET ac... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- -
- Genome
- hg38
- Position
- chr10:43,077,068-43,130,351
- Variant Type
- snv
- Variant (CIViC) (CIViC Variant)
- FUSION
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/1687
Genome browser