chr6:24828262:C>T Detail (hg38) (RIPOR2)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr6:24,828,490-24,828,490 View the variant detail on this assembly version. |
hg38 | chr6:24,828,262-24,828,262 |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_014722.3:c.2603G>A | NP_055537.2:p.Arg868Gln |
NM_001286445.1:c.2453G>A | NP_001273374.1:p.Arg818Gln | |
Ensemble | ENST00000259698.9:c.2603G>A | ENST00000259698.9:p.Arg868Gln |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
JP | HGVD:0.228 |
ToMMo:0.215 | |
NCBN:[No Data.] | |
NCBN(Hondo):[No Data.] | |
NCBN(Ryukyu):[No Data.] | |
East asia | ExAC:0.191 |
Prediction
ClinVar
Clinical Significance |
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Review star | ![]() |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
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2017-08-23 | criteria provided, multiple submitters, no conflicts | not specified |
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Detail |
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2021-08-10 | criteria provided, single submitter | Autosomal recessive nonsyndromic hearing loss 104 |
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Detail |
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2024-01-31 | criteria provided, single submitter | not provided |
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Detail |
CIViC
[No Data.]
DisGeNET
[No Data.]
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_001286445.3(RIPOR2):c.2540G>A (p.Arg847Gln) AND not specified | ClinVar | Detail |
NM_001286445.3(RIPOR2):c.2540G>A (p.Arg847Gln) AND Autosomal recessive nonsyndromic hearing loss 104 | ClinVar | Detail |
NM_001286445.3(RIPOR2):c.2540G>A (p.Arg847Gln) AND not provided | ClinVar | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs9461073 dbSNP
- Genome
- hg38
- Position
- chr6:24,828,262-24,828,262
- Variant Type
- snv
- Reference Allele
- C
- Alternative Allele
- T
- Filtering Status (HGVD)
- PASS
- # of samples (HGVD)
- 892
- Mean of sample read depth (HGVD)
- 17.58
- Standard deviation of sample read depth (HGVD)
- 22.45
- Number of reference allele (HGVD)
- 1377
- Number of alternative allele (HGVD)
- 407
- Allele Frequency (HGVD)
- 0.2281390134529148
- Gene Symbol (HGVD)
- FAM65B
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs9461073
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.2148
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 3600
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
- East Asian Chromosome Counts (ExAC)
- 596
- East Asian Allele Counts (ExAC)
- 114
- East Asian Heterozygous Counts (ExAC)
- 90
- East Asian Homozygous Counts (ExAC)
- 12
- East Asian Allele Frequency (ExAC)
- 0.1912751677852349
- Chromosome Counts in All Race (ExAC)
- 21168
- Allele Counts in All Race (ExAC)
- 4201
- Heterozygous Counts in All Race (ExAC)
- 3315
- Homozygous Counts in All Race (ExAC)
- 443
- Allele Frequency in All Race (ExAC)
- 0.1984599395313681
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