chr15:43007204:G>A Detail (hg38) (UBR1)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr15:43,299,402-43,299,402 View the variant detail on this assembly version. |
hg38 | chr15:43,007,204-43,007,204 |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_174916.2:c.3290C>T | NP_777576.1:p.Thr1097Met |
Ensemble | ENST00000290650.9:c.3290C>T | ENST00000290650.9:p.Thr1097Met |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
JP | HGVD:<0.001 |
ToMMo:0.001 | |
NCBN:[No Data.] | |
NCBN(Hondo):[No Data.] | |
NCBN(Ryukyu):[No Data.] | |
East asia | ExAC:<0.001 |
Prediction
ClinVar
Clinical Significance | Conflicting classifications of pathogenicity |
Review star | ![]() |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
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2024-01-24 | criteria provided, conflicting interpretations | not provided |
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Detail |
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2016-11-07 | criteria provided, single submitter | not specified |
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Detail |
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2022-03-01 | criteria provided, single submitter | Johanson-Blizzard syndrome |
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Detail |
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2022-11-20 | criteria provided, single submitter | UBR1-related disorder |
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Detail |
CIViC
[No Data.]
DisGeNET
[No Data.]
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_174916.3(UBR1):c.3290C>T (p.Thr1097Met) AND not provided | ClinVar | Detail |
NM_174916.3(UBR1):c.3290C>T (p.Thr1097Met) AND not specified | ClinVar | Detail |
NM_174916.3(UBR1):c.3290C>T (p.Thr1097Met) AND Johanson-Blizzard syndrome | ClinVar | Detail |
NM_174916.3(UBR1):c.3290C>T (p.Thr1097Met) AND UBR1-related disorder | ClinVar | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs142285781 dbSNP
- Genome
- hg38
- Position
- chr15:43,007,204-43,007,204
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- A
- Filtering Status (HGVD)
- PASS
- # of samples (HGVD)
- 1210
- Mean of sample read depth (HGVD)
- 86.13
- Standard deviation of sample read depth (HGVD)
- 39.24
- Number of reference allele (HGVD)
- 2418
- Number of alternative allele (HGVD)
- 2
- Allele Frequency (HGVD)
- 8.264462809917355E-4
- Gene Symbol (HGVD)
- UBR1
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs142285781
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.0011
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 19
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
- East Asian Chromosome Counts (ExAC)
- 8654
- East Asian Allele Counts (ExAC)
- 2
- East Asian Heterozygous Counts (ExAC)
- 2
- East Asian Homozygous Counts (ExAC)
- 0
- East Asian Allele Frequency (ExAC)
- 2.3110700254217703E-4
- Chromosome Counts in All Race (ExAC)
- 121382
- Allele Counts in All Race (ExAC)
- 84
- Heterozygous Counts in All Race (ExAC)
- 82
- Homozygous Counts in All Race (ExAC)
- 1
- Allele Frequency in All Race (ExAC)
- 6.920301197871183E-4
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