chr11:47448165:G>A Detail (hg38) (RAPSN)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr11:47,469,717-47,469,717 View the variant detail on this assembly version. |
hg38 | chr11:47,448,165-47,448,165 |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_005055.4:c.193-15C>T | |
NM_032645.4:c.193-15C>T | ||
Ensemble | ENST00000298854.7:c.193-15C>T |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
JP | HGVD:0.018 |
ToMMo:0.019 | |
NCBN:[No Data.] | |
NCBN(Hondo):[No Data.] | |
NCBN(Ryukyu):[No Data.] | |
East asia | ExAC:0.034 |
Prediction
ClinVar
Clinical Significance |
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Review star | ![]() |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
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2016-03-11 | criteria provided, multiple submitters, no conflicts | not specified |
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Detail |
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2021-07-10 | criteria provided, multiple submitters, no conflicts | congenital myasthenic syndrome 11 |
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Detail |
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2018-03-06 | criteria provided, single submitter | Fetal akinesia deformation sequence 1 |
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Detail |
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2020-09-16 | no assertion criteria provided | congenital myasthenic syndrome |
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Detail |
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2021-07-10 | criteria provided, single submitter | Fetal akinesia deformation sequence 2 |
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Detail |
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2024-02-01 | criteria provided, single submitter | congenital myasthenic syndrome 11,Fetal akinesia deformation sequence 1 |
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Detail |
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2024-02-01 | criteria provided, single submitter | congenital myasthenic syndrome 11,Fetal akinesia deformation sequence 1 |
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Detail |
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.120 | MYASTHENIC SYNDROME, CONGENITAL, Ie | NA | CLINVAR | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_005055.5(RAPSN):c.193-15C>T AND not specified | ClinVar | Detail |
NM_005055.5(RAPSN):c.193-15C>T AND Congenital myasthenic syndrome 11 | ClinVar | Detail |
NM_005055.5(RAPSN):c.193-15C>T AND Fetal akinesia deformation sequence 1 | ClinVar | Detail |
NM_005055.5(RAPSN):c.193-15C>T AND Congenital myasthenic syndrome | ClinVar | Detail |
NM_005055.5(RAPSN):c.193-15C>T AND Fetal akinesia deformation sequence 2 | ClinVar | Detail |
NM_005055.5(RAPSN):c.193-15C>T AND multiple conditions | ClinVar | Detail |
NM_005055.5(RAPSN):c.193-15C>T AND multiple conditions | ClinVar | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs45547231 dbSNP
- Genome
- hg38
- Position
- chr11:47,448,165-47,448,165
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- A
- Filtering Status (HGVD)
- PASS
- # of samples (HGVD)
- 826
- Mean of sample read depth (HGVD)
- 25.72
- Standard deviation of sample read depth (HGVD)
- 12.69
- Number of reference allele (HGVD)
- 1623
- Number of alternative allele (HGVD)
- 29
- Allele Frequency (HGVD)
- 0.017554479418886198
- Gene Symbol (HGVD)
- RAPSN
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs45547231
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.019
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 318
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16758
- East Asian Chromosome Counts (ExAC)
- 8318
- East Asian Allele Counts (ExAC)
- 279
- East Asian Heterozygous Counts (ExAC)
- 275
- East Asian Homozygous Counts (ExAC)
- 2
- East Asian Allele Frequency (ExAC)
- 0.03354171675883626
- Chromosome Counts in All Race (ExAC)
- 115732
- Allele Counts in All Race (ExAC)
- 13149
- Heterozygous Counts in All Race (ExAC)
- 11575
- Homozygous Counts in All Race (ExAC)
- 787
- Allele Frequency in All Race (ExAC)
- 0.11361594027580962
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