chr8:11643553:G>T Detail (hg19) (NEIL2)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr8:11,643,553-11,643,553 |
hg38 | chr8:11,786,044-11,786,044 View the variant detail on this assembly version. |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_145043.2:c.770G>T | NP_659480.1:p.Arg257Leu |
NM_001135747.1:c.587G>T | NP_001129219.1:p.Arg196Leu | |
NM_001135746.1:c.770G>T | NP_001129218.1:p.Arg257Leu |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Frequency
JP | HGVD:0.211 |
ToMMo:0.231 | |
NCBN:[No Data.] | |
NCBN(Hondo):[No Data.] | |
NCBN(Ryukyu):[No Data.] | |
East asia | ExAC:0.224 |
Prediction
ClinVar
Clinical Significance | |
Review star | [No Data.] |
Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
<0.001 | Impaired cognition | Dispersed association effects involving MutYH(His324Gln), MutYH(Met22Val), PolB(... | BeFree | 21884718 | Detail |
<0.001 | Impaired cognition | Dispersed association effects involving MutYH(His324Gln), MutYH(Met22Val), PolB(... | BeFree | 21884718 | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
Dispersed association effects involving MutYH(His324Gln), MutYH(Met22Val), PolB(Pro242Arg) and NEIL2... | DisGeNET | Detail |
Dispersed association effects involving MutYH(His324Gln), MutYH(Met22Val), PolB(Pro242Arg) and NEIL2... | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- Genome
- hg19
- Position
- chr8:11,643,553-11,643,553
- Variant Type
- snv
- Reference Allele
- G
- Alternative Allele
- T
- Filtering Status (HGVD)
- PASS
- # of samples (HGVD)
- 1018
- Mean of sample read depth (HGVD)
- 26.56
- Standard deviation of sample read depth (HGVD)
- 25.50
- Number of reference allele (HGVD)
- 1607
- Number of alternative allele (HGVD)
- 429
- Allele Frequency (HGVD)
- 0.2107072691552063
- Gene Symbol (HGVD)
- NEIL2
- ToMMo VCF FILTER column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- PASS
- Total VCF ID column value (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- rs8191664
- Allele frequency, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 0.2314
- Allele count in genotypes, for each ALT allele (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 3878
- Total number of alleles in called genotypes (ToMMo 8.3KJPN Allele Frequency Panel(v20200831))
- 16760
- East Asian Chromosome Counts (ExAC)
- 8644
- East Asian Allele Counts (ExAC)
- 1939
- East Asian Heterozygous Counts (ExAC)
- 1497
- East Asian Homozygous Counts (ExAC)
- 221
- East Asian Allele Frequency (ExAC)
- 0.22431744562702452
- Chromosome Counts in All Race (ExAC)
- 121302
- Allele Counts in All Race (ExAC)
- 4421
- Heterozygous Counts in All Race (ExAC)
- 3857
- Homozygous Counts in All Race (ExAC)
- 282
- Allele Frequency in All Race (ExAC)
- 0.0364462251240705
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