chr13:20763503:T>C Detail (hg19) (GJB2)
Information
Genome
Assembly | Position |
---|---|
hg19 | chr13:20,763,503-20,763,503 |
hg38 | chr13:20,189,364-20,189,364 View the variant detail on this assembly version. |
HGVS
Type | Transcript | Protein |
---|---|---|
RefSeq | NM_004004.5:c.218A>G | NP_003995.2:p.His73Arg |
Ensemble | ENST00000382848.5:c.218A>G | ENST00000382848.5:p.His73Arg |
ENST00000382844.2:c.218A>G | ENST00000382844.2:p.His73Arg |
Summary
MGeND
Clinical significance | |
Variant entry | |
GWAS entry | |
Disease area statistics | Show details |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
Clinical significance | Last evaluated | Review status | Condition | Origin | Links |
---|---|---|---|---|---|
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1999-04-17 | no assertion criteria provided | palmoplantar keratoderma-deafness syndrome |
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Detail |
CIViC
[No Data.]
DisGeNET
Score | Disease name | Description | Source | Pubmed | Links |
---|---|---|---|---|---|
0.482 | Mutilating keratoderma | Here, we report on a family with a novel GJB2 mutation (p.His73Arg) causing a sy... | BeFree | 17993581 | Detail |
0.481 | Palmoplantar Keratoderma with Deafness | NA | CLINVAR | Detail |
Annotation
Annotations
Descrption | Source | Links |
---|---|---|
NM_004004.6(GJB2):c.218A>G (p.His73Arg) AND Palmoplantar keratoderma-deafness syndrome | ClinVar | Detail |
Here, we report on a family with a novel GJB2 mutation (p.His73Arg) causing a syndrome of focal palm... | DisGeNET | Detail |
NA | DisGeNET | Detail |
Overlapped Transcript Coordinates
Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
---|
Overlapped Transcript
Gene | Transcript ID | Chromosome | Start | Stop | Links |
---|
- Gene
- -
- dbSNP
- rs121912968 dbSNP
- Genome
- hg19
- Position
- chr13:20,763,503-20,763,503
- Variant Type
- snv
- Reference Allele
- T
- Alternative Allele
- C
Genome browser