FGFR2 AMPLIFICATION Detail (hg38) (FGFR2)
Information
Genome
| Assembly | Position |
|---|---|
| hg19 | chr10:123,239,371-123,357,917 View the variant detail on this assembly version. |
| hg38 | chr10:121,479,857-121,598,403 |
Summary
MGeND
| Clinical significance | |
| Variant entry | |
| GWAS entry | |
| Disease area statistics | Show details |
ClinVar
| Clinical Significance | |
| Review star | [No Data.] |
| Show details | |
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
| Disease | Drug | EL | ET | ED | CS | VO | TR | Pubmed | Links |
|---|---|---|---|---|---|---|---|---|---|
| breast cancer | Dovitinib | B |
Predictive
|
Supports
|
Sensitivity/Response |
N/A
|
2 | 23658459 | Detail |
| stomach carcinoma | FGFR Inhibitor AZD4547 | B |
Predictive
|
Supports
|
Sensitivity/Response |
N/A
|
3 | 27179038 | Detail |
DisGeNET
[No Data.]
Annotation
Annotations
| Descrption | Source | Links |
|---|---|---|
| Dovitinib was evaluated in-vitro, in xenograft and in a phase 2 study. Dovitinib inhibited prolifera... | CIViC Evidence | Detail |
| Nine patients with FGFR2-amplified gastroesophageal cancer were treated with AZD4547. Of these 9 pa... | CIViC Evidence | Detail |
Overlapped Transcript Coordinates
| Gene | Transcript ID | Exon Number | Chromosome | Start | Stop | Type | Amino Mutation | Transcript Position | Links |
|---|
Overlapped Transcript
| Gene | Transcript ID | Chromosome | Start | Stop | Links |
|---|
- Gene
- FGFR2
- Genome
- hg38
- Position
- chr10:121,479,857-121,598,403
- Variant Type
- cnv
- Variant (CIViC) (CIViC Variant)
- AMPLIFICATION
- Transcript 1 (CIViC Variant)
- ENST00000457416.2
- Variant URL (CIViC Variant)
- https://civic.genome.wustl.edu/links/variants/629
Genome browser