MAP2K4 mitogen-activated protein kinase kinase 4
Information
- Symbol
- MAP2K4
- Type
- protein-coding
- Description
- mitogen-activated protein kinase kinase 4
- Entrez Gene ID
- 6416
- Genome
- hg19
- Position
- chr17:11,924,151-12,047,147
- Genome
- hg38
- Position
- chr17:12,020,834-12,143,830
- MIM
- 601335 OMIM
- HGNC
- HGNC:6844 HGNC
- Ensembl
- ENSG00000065559 Ensembl
- Links
- NCBI Gene Cards OncoKB
Clinical Significance
| MGeND | ClinVar | |
|---|---|---|
| not provided | 38 | 2 |
| other | 0 | 2 |
| Uncertain significance | 4 | 28 |
Ranking
| ClinVar | |
|---|---|
 |
0 |
 |
0 |
 |
0 |
 |
28 |
 |
2 |
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
Locus Zoom
Variants
Search Word
| Target data | : |
MGeND data only
|
| Category | : |
|
| Search word | : | |
| Filtering | : |
| Variant name | Gene | AA change | CDS | Japanese frequency |
TogoVar | MGeND | Genome | ClinVar | CIViC evidence | DisGeNET entry | COSMIC occurrence |
Prediction | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | Entry | Origin | Annotation | |||||||||||
Search Word
| Target data | : |
MGeND data only
|
| Category | : |
|
| Search word | : | |
| Filtering | : |
| Name | MGeND | Type | Genome | Size | Chromosome | Start | Stop | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | ||||||||||||||
Search Word
| Target data | : |
MGeND data only
|
| Category | : |
|
| Search word | : | |
| Filtering | : |
| Name | MGeND | Type | Genome | Gene symbol | Chromosome | Genomic start | Genomic stop | Strand | Ref | Alt | ClinVar | Origin | Entry | CIViC evidence | DisGeNET entry | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Entry | Origin | Type | Annotation | |||||||||||||||
| Type | ID |
|---|---|
| SYNONYM | JNKK |
| SYNONYM | JNKK1 |
| SYNONYM | MAPKK4 |
| SYNONYM | MEK4 |
| SYNONYM | MKK4 |
| SYNONYM | PRKMK4 |
| SYNONYM | SAPKK-1 |
| SYNONYM | SAPKK1 |
| SYNONYM | SEK1 |
| SYNONYM | SERK1 |
| SYNONYM | SKK1 |
| MIM | 601335 OMIM |
| HGNC | HGNC:6844 HGNC |
| Ensembl | ENSG00000065559 Ensembl |
| AllianceGenome | HGNC:6844 |
| Descrption | Source | Links |
|---|
| ID | Genome | Chromosome | Start | End | Length |
|---|---|---|---|---|---|
| ENST00000353533.10 | hg38 | chr17 | 12,020,877 | 12,143,828 | 122,952 |
| ENST00000415385.7 | hg38 | chr17 | 12,020,834 | 12,143,830 | 122,997 |
| ENST00000415385.7 | hg19 | chr17 | 11,924,151 | 12,047,147 | 122,997 |
| ENST00000353533.10 | hg19 | chr17 | 11,924,194 | 12,047,145 | 122,952 |
| Key | Value |
|---|---|
| strand | + |
| start | 11,924,134 |
| Gene Symbol | MAP2K4 |
| Entrez GeneId | 6,416 |
| Chr Band | 17p11.2 |
| end | 12,047,147 |
| chr | chr17 |
| Name | mitogen-activated protein kinase kinase 4 |
Genome browser