MAP2K2 mitogen-activated protein kinase kinase 2

Information
Symbol
MAP2K2
Type
protein-coding
Description
mitogen-activated protein kinase kinase 2
Entrez Gene ID
5605
Genome
hg19
Position
chr19:4,090,319-4,124,119
Genome
hg38
Position
chr19:4,090,321-4,124,122
MIM
601263 OMIM
HGNC
HGNC:6842 HGNC
Ensembl
ENSG00000126934 Ensembl
Links
NCBI Gene Cards OncoKB
Clinical Significance
MGeND ClinVar
Pathogenic 14 22
Likely pathogenic 2 44
Benign 4 240
Likely benign 0 632
Conflicting classifications of pathogenicity 0 74
not provided 34 0
Uncertain significance 1 630
Ranking
ClinVar
0
96
396
996
20
Frequency
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
EXAC_EAS
EXAC_EAS
HGVD
HGVD
TOMMO
TOMMO
Gene
Position
Disease area statistics
Locus Zoom
Variants
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Variant name Gene AA change CDS Japanese
frequency		 TogoVar MGeND Genome ClinVar CIViC evidence DisGeNET entry COSMIC
occurrence		 Prediction
Entry Origin Type Annotation Entry Origin Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Size Chromosome Start Stop Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
Search Word
Target data :
MGeND data only
Category :
Search word :
Filtering :
Name MGeND Type Genome Gene symbol Chromosome Genomic start Genomic stop Strand Ref Alt ClinVar Origin Entry CIViC evidence DisGeNET entry
Entry Origin Type Annotation
TypeID
SYNONYM CFC4
SYNONYM MAPKK2
SYNONYM MEK2
SYNONYM MKK2
SYNONYM PRKMK2
MIM 601263 OMIM
HGNC HGNC:6842 HGNC
Ensembl ENSG00000126934 Ensembl
AllianceGenome HGNC:6842
DescrptionSourceLinks
IDGenomeChromosomeStartEndLength
ENST00000262948.10 hg38 chr19 4,090,321 4,124,122 33,802
ENST00000262948.10 hg19 chr19 4,090,319 4,124,119 33,801
KeyValue
strand-
start4,090,319
Gene SymbolMAP2K2
Entrez GeneId5,605
Chr Band19p13.3
end4,124,125
chrchr19
Namemitogen-activated protein kinase kinase 2
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